 Basic Sciences | Clinical Sciences | Cancer Prevention & Control | Prostate Cancer SPORE | R.A.D.A.R. |
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Research Programs > Basic Sciences Research Division
Vascular Biology Research Team: Awad, Beitel, Chandel, Chew, Crawford, Dean, Gonzalez, Kibbe, Kramer, Mustoe, Schnaper, Schumacker, Volpert Acquisition of a vascular supply enables tumors to procure nutrients necessary for continued growth and provides an avenue of escape for metastasizing tumor cells. Conversely, angiogenesis inhibition has provided a promising new target for novel therapeutic approaches to shrink primary tumor size and prevent metastasis. Research in the vascular biology group is focused on basic research on tube formation, endothelial cell survival and hypoxia response (Beitel, Chandel, Chew, Kibbe, Mustoe, Schnaper, Schumacher). Translational studies investigate both mechanistic and therapeutic analysis of novel proteins with anti-angiogenic properties and the role of the immune response in aberrant vasculogenesis (Awad, Crawford, Dean, Gonzalez, Kramer, Volpert). |
