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Research Programs > Basic Sciences Research Division

Cancer Cell Biology

Program Leader: Andreas Matouschek, PhD
Program Co-Leader: Hiroaki Kiyokawa, MD, PhD

Membership Roster: Cancer Cell Biology Membership Roster

The Cancer Cell Biology program of the Robert H. Lurie Comprehensive Cancer Center focuses on basic research in cell biology. This Program was established because of the significant increase in strength in this research area at Northwestern University through hiring and growth of existing faculty. Andreas Matouschek, PhD, and Hiroaki Kiyokawa, MD, PhD, lead the program and are located on the Evanston and Chicago campus respectively. The leadership team was selected to complement each other with respect to their scientific and medical backgrounds and to fully integrate the program over both of Northwestern's campuses. The goal of this program is to increase the amount and quality of the cancer research in cell biology at Northwestern by supporting existing research efforts in this area and by attracting high quality basic researchers to focus their research to a cancer theme. The program consists of 28 faculty from five departments and two schools. Between January 2001 and September 2006 there have been 343 cancer-relevant publications from the current program members. Fifty-Nine (17%) of these publications represent intra-programmatic collaborations and 80 (23%) represent inter-programmatic collaborations. Total current cancer-relevant peer-reviewed funding is $8,231,819 (direct) with $1,863,761 (direct) from NCI and $6,368,058 (direct) from other peer-reviewed sources. The research of program members falls into four broad areas: posttranscriptional regulation of protein function, regulation of subcellular localization of DNA and proteins, the control of cell fate determination, and cancer animal models and therapeutics. These topics play a fundamental role in the control of cell growth and differentiation. Program members study how these mechanisms functional normally and how that function goes awry during neoplastic transformation. An understanding of these mechanisms leads to the development of new technologies to be used in cancer therapy and research.

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